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While gastrointestinal side effects like nausea and diarrhea are well-documented, some patients report experiencing leg cramps during treatment

While tirzepatide made history as the first dual GIP/GLP-1 receptor agonist to receive FDA approval, retatrutide pushes the pharmacological envelope further with triple receptor agonism that adds glucagon receptor activation

Some patients achieve their goals at 0.5 mg weekly of semaglutide, while others require the full 2.4 mg

Though biosimilar competition in Europe increased, allowing insulin prices to be low, branded drugs have always been the order of the day